Abstract Search

ey0016.5-13 | Basic Science - Growth Plate | ESPEYB16

5.13. Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

JC Lui , YH Jee , P Garrison , JR Iben , S Yue , M Ad , Q Nguyen , B Kikani , Y Wakabayashi , J Baron

Abstract: PLoS Biol. 2018 Jul 23;16(7):e2005263.In brief: In this article, Lui et al, make important observations related to the fundamental limits of longitudinal bone growth implicating the growth plate senescence program as a major regulator of bone size.Comment: A persons right and left arms almost always grow to the same length, bu...

0 shares

ey0016.14-13 | (1) | ESPEYB16

14.13. Effect of genetic diagnosis on patients with previously undiagnosed disease

K Splinter , DR Adams , CA Bacino , HJ Bellen , JA Bernstein , AM Cheatle-Jarvela , CM Eng , C Esteves , WA Gahl , R Hamid , HJ Jacob , B Kikani , DM Koeller , IS Kohane , BH Lee , J Loscalzo , X Luo , AT McCray , TO Metz , JJ Mulvihill , SF Nelson , CGS Palmer , JA, 3rd Phillips , L Pick , JH Postlethwait , C Reuter , V Shashi , DA Sweetser , CJ Tifft , NM Walley , MF Wangler , M Westerfield , MT Wheeler , AL Wise , EA Worthey , S Yamamoto , EA Ashley

To read the full abstract: N Engl J Med 2018;379:21312139.The authors reviewed data on 1519 patients referred to the Undiagnosed Diseases Network (UDN), a US NIH funded network linking seven clinical sites. 53% of patients were female and their symptoms were neurologic (40%), musculoskeletal (10%), immunological (7%), gastrointestinal (7%), or rheumatological (6%). Of the 38...

0 shares

ESPE Yearbook of Paediatric Endocrinology

5.13. Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

14.13. Effect of genetic diagnosis on patients with previously undiagnosed disease

BiosciAbstracts